Type 2 diabetes can also be multigenerational like MODY

Type 2 diabetes can also be multigenerational like MODY

First UK survey of paediatric type 2 diabetes and MODY.

AIMS To estimate the UK prevalence of childhood type 2 diabetes and maturity onset diabetes of the young (MODY), and distinguish them from each other and from type 1 diabetes. METHODS The British Society for Paediatric Endocrinology and Diabetes Clinical Trials/Audit Group undertook a cross-sectional questionnaire survey of all paediatric diabetes centres during 2000, collecting data on all c...

Type 2 Diabetes Can Be Prevented With Early Pharmacological Intervention

In the U.S., ∼ 21 × 10(6) individuals have type 2 diabetes, and twice as many have impaired glucose tolerance (IGT). Approximately 40-50% of individuals with IGT will progress to type 2 diabetes over their lifetime. Therefore, treatment of high-risk individuals with IGT to prevent type 2 diabetes has important medical, economic, social, and human implications. Weight loss, although effective in...

Obesity and Type 2 Diabetes: What Can Be Unified and What Needs to Be Individualized?

OBJECTIVE This report examines what is known about the relationship between obesity and type 2 diabetes and how future research in these areas might be directed to benefit prevention, interventions, and overall patient care. RESEARCH DESIGN AND METHODS An international working group of 32 experts in the pathophysiology, genetics, clinical trials, and clinical care of obesity and/or type 2 dia...

Non-ketotic diabetes in Saudi Arabian youths: MODY or early onset of type 2 diabetes?

Background: Non-ketotic diabetes mellitus is commonly seen in young Saudi Arabian adults. This could be either early onset of typical type 2 diabetes, T2DM or maturity-onset diabetes of the young, MODY. Consanguinity is also prevalent and clouds the inheritance pattern of the disease. Distinction between the two on clinical grounds alone is not always possible. Materials and Method: Diabetic pa...